Table 3.

Cumulative PPV/Sensitivity/Specificity (%) for CIN3+ in the triage of hrHPV-positive women

hrHPV types	Primary type	For the new type		Cumulative types
	PPV (%)	CIN3+/HPV+	PPV (%)	CIN3+/HPV+	PPV (%)	SEN (%)	SPE (%)
16	18.0	184/1020	18.0	184/1020	18.0	73.3	66.3
33	15.3	17/119	14.3	201/1139	17.6	80.1	62.2
31	8.2	11/127	8.7	212/1266	16.7	84.5	57.6
58	8.5	21/292	7.2	233/1558	15.0	92.8	46.7
45	8.8	1/32	3.1	234/1590	14.7	93.2	45.4
66	2.8	2/74	2.7	236/1664	14.2	94.0	42.5
52	6.0	6/270	2.2	242/1934	12.5	96.4	31.9
18	3.5	5/265	1.9	247/2199	11.2	98.4	21.4
35	7.1	1/59	1.7	248/2258	11.0	98.8	19.1
56	4.5	1/84	1.2	249/2342	10.6	99.2	15.7
51	1.7	1/131	0.8	250/2473	10.2	99.6	10.5
68	4.0	1/121	0.8	251/2594	9.7	100.0	5.7
59	1.0	0/56	0.0	251/2650	9.5	100.0	3.4
39	2.2	0/85	0.0	251/2735	9.2	100.0	0.0

Abbreviations: CIN3+ cervical intraepithelial neoplasia 3 or worse, SEN sensitivity, SPE specificity, PPV positive predictive value