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Co-trimoxazole treatment response of patients with PCP according to DHPS mutations in the patient's P. carinii isolates
| DHPS type | No. (%) of patients
|
||
|---|---|---|---|
| Treatment failure | Treatment success | Total | |
| Mutant | 4 (100)a | 0 (0)b | 4 |
| Wild type | 2 (11.1)a | 16 (88.9) | 18 |
P = 0.002.
Due to skin eruptions, two patients (patients 5 and 6) whose isolates had DHPS mutations were switched from co-trimoxazole to intravenous pentamidine and were not included as treatment successes.
