Table 1.
Detailed baseline characteristics of the enrolled patients
| Characteristic | Total (n = 504) | > 1year (n = 252) | ≤ 1year (n = 252) | P value |
|---|---|---|---|---|
| Age, years, n (%) | 59.61 (9.49) | 59.69 (9.48) | 59.52 (9.51) | 0.844 |
| Gender, n (%) | 1.000 | |||
| Male | 324 (64.30) | 162 (64.30) | 162 (64.30) | |
| Female | 180 (35.70) | 90 (35.70) | 90 (35.70) | |
| Tumor stage, n (%) | 1.000 | |||
| I | 14 (2.80) | 7 (2.80) | 7 (2.80) | |
| II | 62 (12.30) | 31 (12.30) | 31 (12.30) | |
| III | 164 (32.50) | 82 (32.50) | 82 (32.50) | |
| IV | 264 (52.40) | 132 (52.40) | 132 (52.40) | |
| Chronic disease (Yes), n (%) | 167 (33.10) | 89 (35.30) | 78 (31.00) | 0.344 |
| Family history (Yes), n (%) | 76 (15.10) | 37 (14.70) | 39 (15.50) | 0.901 |
| Smoking, n (%) | 260 (51.60) | 125 (49.60) | 135 (53.60) | 0.422 |
| Drinking, n (%) | 143 (28.40) | 64 (25.40) | 79 (31.30) | 0.167 |
| Tea consumption (Yes), n (%) | 149 (29.60) | 77 (30.60) | 72 (28.60) | 0.696 |
| Nutrition support (Yes), n (%) | 199 (39.50) | 85 (33.70) | 114 (45.20) | 0.011 |
| Total protein, g/L | 66.45 (7.79) | 67. 63 (6.86) | 65.28 (8.47) | 0.001 |
| Albumin, g/L | 36.69 (5.84) | 38.30 (5.92) | 35.09 (5.32) | <0.001 |
| TBIL, median (IQR), g/L | 11.00 [8.00, 15.20] | 10.55 [8.00, 14.35] | 11.20 [8.07, 16.33] | 0.058 |
| AST, median (IQR), U/L | 22.00 [17.00, 30.02] | 21.00 [17.00, 28.38] | 22.95 [17.20, 32.00] | 0.093 |
| ALT, median (IQR), U/L | 18.80 [13.00, 29.38] | 18.80 [13.47, 29.00] | 18.45 [12.80, 31.15] | 0.970 |
| Hb, g/L | 116.83 (19.72) | 120.38 (17.97) | 113.29 (20.76) | <0.001 |
| WBC, 109/L | 7.15 (3.68) | 6.45 (3.21) | 7.86 (3.98) | <0.001 |
| Neutrophil count, 109/L | 4.98 (3.88) | 4.36 (3.90) | 5.59 (3.77) | <0.001 |
| Lymphocyte count, 109/L | 1.43 (0.71) | 1.53 (0.65) | 1.33 (0.76) | 0.001 |
| RBC, 1012/L | 4.03 (0.67) | 4.16 (0.59) | 3.90 (0.72) | <0.001 |
| PLT, 109/L | 249.35 (106.74) | 237.52 (95.92) | 261.17 (115.56) | 0.013 |
| BMI, kg/m2 | 20.66 (3.13) | 21.18 (3.26) | 20.15 (2.90) | <0.001 |
| HGS, kg | 23.05 (9.12) | 24.25 (8.50) | 21.85 (9.56) | 0.003 |
| TSF, mm | 13.40 (7.18) | 14.53 (7.37) | 12.27 (6.83) | <0.001 |
| MAC, cm | 24.83 (3.50) | 25.22 (3.66) | 24.44 (3.29) | 0.012 |
| Surgery, n (%) | 127.00 (25.20) | 67.00 (26.60) | 60.00 (23.80) | 0.530 |
| Chemotherapy, n (%) | 279.00 (55.40) | 155.00(61.50) | 124.00 (49.20) | 0.007 |
| Radiotherapy, n (%) | 28.00(5.60) | 9.00 (3.60) | 19.00 (7.50) | 0.080 |
Notes: Continuous variables were represented by mean ± standard deviations (SDs), among them, TBIL, AST, ALT were represented by median and interquartile range. Categorical variables were represented by numbers and percentages. Differences in baseline characteristics were compared using the chi-square test, t-test (conform to the normal distribution), or Wilcoxon rank sum test (not conform to the normal distribution). TBIL: total bilirubin; AST: aspartic transaminase; ALT: alanine transaminase; Hb: hemoglobin; WBC: white blood cell; RBC: red blood cell; PLT: platelet count; BMI: body mass index; HGS: hand grip strength; TSF: triceps skin fold; MAC: mid-upper arm circumference.