Table 1.
The relationship between CGI-58 and clinicopathologic characteristics in patients with endometrial cancer.
| Characteristics | TCGA | Cohort 2 | ||||||
|---|---|---|---|---|---|---|---|---|
| n | Low (%) | High (%) | P | n | Low (%) | High (%) | P | |
| Age | 0.605 | 80 | 0.152 | |||||
| <=60 | 206 | 101 (49) | 105 (51) | 54 | 30 (55.6) | 24 (44.4) | ||
| >60 | 343 | 176 (51) | 167 (49) | 26 | 10 (38.5) | 16 (61.5) | ||
| Missing information | 3 | |||||||
| Histology | 0.025* | 0.176 | ||||||
| Endometrioid-type | 410 | 195 (47.6) | 215 (52.4) | 70 | ||||
| serous carcinoma | 142 | 83 (58.5) | 59 (41.5) | 10 | 37 (52.9) | 33 (47.1) | ||
| 3 (30) | 7 (70) | |||||||
| FIGO Stage | 0.055 | 0.210 | ||||||
| I-II | 393 | 187 (47.6) | 206 (52.4) | 68 | 36 (52.9) | 32 (47.1) | ||
| III-IV | 159 | 90 (56.6) | 69 (43.4) | 12 | 4 (33.3) | 8 (66.7) | ||
| Differentiation | <0.001* | 0.004* | ||||||
| 1 | 109 | 74 (67.9) | 35 (32.1) | 32 | 23 (71.9) | 9 (28.1) | ||
| 2 | 120 | 65 (54.2) | 55 (45.8) | 26 | 11 (42.3) | 15 (57.7) | ||
| 3 | 323 | 138 (42.7) | 185 (57.3) | 22 | 6 (27.3) | 16 (72.7) | ||
| Death | 0.092 | 0.01* | ||||||
| No | 507 | 249 (49.1) | 258 (50.9) | 65 | 37 (56.9) | 28 (43.1) | ||
| Yes | 45 | 28 (62.2) | 17 (37.8) | 15 | 3 (20) | 12 (80) | ||
Abbreviations: n = number of patients;