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. 2021 Dec 28;13(12):530–540. doi: 10.14740/jocmr4637

Table 1. Summary of the Results of the Primary and Subgroup Analysis.

HCC positive (cases) HCC negative (controls) Random-effect odds ratio (95% confidence interval)
Primary analysis
  Relationship between H. pylori and HCC 561/866 (64.78%) 1,718/3,585 (47.92%) 4.75 (3.06 - 7.37)
Subgroup analysis
  H. pylori and HCV coinfection 168/422 (39.81%) 83/740 (11.21%) 12.76 (4.13 - 39.41)
  H. pylori infection only without HCV 36/303 (11.88%) 79/495 (15.95%) 0.54 (0.11 - 2.63)
  HCV only without H. pylori 84/262 (32.06%) 141/485 (29.07%) 2.21 (0.70 - 6.94)

HCC: hepatocellular carcinoma; HCV: hepatitis C virus; H. pylori: Helicobacter pylori.