Fig. 6.

Arthritis score A and paw volume B for DSP and DXP-NPs treated animals and non-treated animals after the induction of the disease and during the treatment period. The treated animals received three intravenous injections of 1 mg/kg DXM every 2 days (arrows and dotted lines) and the non-treated animals received a similar volume of PBS. The rheumatoid arthritis was induced by immunization of the mice with collagen at days 0 and 21. The treatments were administered on days 32, 34, and 36. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001