Table 2.
Minimal Inhibitory Concentration under aerobic and anaerobic conditions
MIC μg/mL | Vanco-mycin | Linezolid | Fusidic Acid *,† (n=91) | Rifampin* (n=82) |
TMP-SMX | Clindamycin* (n=69) |
---|---|---|---|---|---|---|
Aerobic | 0.74±0.02 | 1.14±0.06 | 0.09±0.007 | 0.04±0.02 | 0.04±0.02 | 0.06±0.002 |
Anaerobic | 0.58±0.02 | 1.10±0.07 | 0.04±0.006 | 0.03±0.014 | 0.08±0.02 | 0.09±0.006 |
p-value | <0.0001 | 0.63 | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
MIC in μg/mL reported as mean ± standard error of the mean of triplicate testing for incident and chronic isolates.
Pairs with one or both resistant isolates per CLSI breakpoints were excluded.
EUCAST criteria as CLSI breakpoints for fusidic acid are not available. Comparisons between aerobic and anaerobic conditions are by Wilcoxon matched pairs signed rank test.