Table 5.

Univariate logistic regression of vaccine acceptance among individuals with serious comorbidities (n=21,294) using Inspire between January 15, 2021 and February 22, 2021.

Variable			Odds ratio (95% CI)		P value
Routine influenza vaccine			1.24 (1.23-1.25)		<.001
Trust in responsible development of COVID vaccine			2.07 (2.05-2.09)		<.001
Prior COVID infection			0.93 (0.92-0.94)		<.001
Political leaning
	Conservative political leaning (reference)	-a		-
	Independent	1.12 (1.10-1.13)		.003
	Liberal leaning	1.14 (1.12-1.15)		<.001
Residence (United States vs outside the United States)			1.03 (1.02-1.04)		<.001
Age
	Age below the median (reference)	-		-
	Median age	0.99 (0.98-0.99)		<.001
	Age above the median	1.12 (1.11-1.13)		<.001
Education level
	High school and less (reference)	-		-
	Some college, associate degree	1.03 (1.03-1.04)		<.001
	At least a college degree	1.04 (1.02-1.06)		<.001
Smoking status			1.01 (1.00-1.02)		.17
Gender			0.98 (0.97-0.99)		.001
Cancer diagnosis			1.03 (1.02-1.04)		.001
Mask wearing			1.02 (1.01-1.03)		<.001

^aReference category.