Unstable switch (4B) |
Unstable CHE-1 switch, average lifetime of ~10 days |
|
|
Number of CHE-1 protein molecules |
900 |
|
Number of che-1 mRNA molecules |
7 |
|
Number of che-1 promoters |
1 |
|
Number of target genes |
500 |
|
Binding rate of CHE-1 on che-1 or target gene promoters |
0.03 s–1
|
|
Unbinding rate of CHE-1 from che-1 promoter |
100 s–1
|
|
Unbinding rate of CHE-1 from target gene promoters |
100 s–1
|
|
che-1 mRNA production rate |
0.0302 s–1
|
|
che-1 mRNA degradation rate |
0.00083 s–1
|
|
CHE-1 protein production rate |
0.0274 s–1
|
|
CHE-1 protein degradation rate |
0.00024 s–1
|
Stable switch (4B) |
Highly stable switch, slower unbinding rate of CHE-1 from its own promoter
|
|
|
Unbinding rate of CHE-1 from che-1 promoter |
0.1 s–1
|
|
che-1 mRNA production rate |
0.0059 s–1
|
|
CHE-1 protein production rate |
0.0261 s–1
|
|
CHE-1 protein degradation rate |
0.00023 s–1
|
Stable switch (4E) |
Highly stable switch, depleted to 100 CHE-1
|
|
|
Unbinding rate of CHE-1 from che-1 promoter |
0.1 s–1
|
|
che-1 mRNA production rate |
0.0059 s–1
|
|
CHE-1 protein degradation rate |
0.0019 s–1
|
|
CHE-1 protein production rate |
0.024 s–1
|
|
Target mRNA degradation rate |
0.0008 s–1
|
|
Target mRNA production rate |
0.09 s–1
|
Unstable switch (4E) |
Unstable switch, depleted to 100 CHE-1
|
|
|
Unbinding rate of CHE-1 from che-1 promoter |
10 s–1
|
|
Unbinding rate of CHE-1 from target gene promoters |
10 s–1
|
|
CHE-1 protein degradation rate |
0.00076 s–1
|
|
CHE-1 protein production rate |
0.026 s–1
|
|
Target mRNA degradation rate |
0.0004 s–1
|
|
Target mRNA production rate |
0.016 s–1
|
|
|
|