Parameter	Description	Value
Common
$f_{O,C}$	Binding rate of CHE-1 on che-1 promoter	0.03 s–1
$f_O$	Binding rate of CHE-1 on target gene promoters	0.03 s–1
$f_{O,H}$	Binding rate of HD-TF on che-1 promoter	0.03 s–1
$b_O$	Unbinding rate of CHE-1 and HD-TF from promoter	100 s–1
$f_M$	che-1 mRNA production rate	0.0085 s–1
$b_M$	che-1 mRNA degradation rate	0.00083 s–1
$f_C$	CHE-1 protein production rate	0.0198 s–1
$b_C$	CHE-1 protein degradation rate	0.00032 s–1
$f_{M,0}$	CHE-1 independent che-1 mRNA production rate	0.005 s–1
Model 1
$b_{O,s}$	Slow unbinding rate of CHE-1/HD-TF from complex on promoter	0.1 s–1
Model 2
$f_M$	che-1 mRNA production rate upon induction by CHE-1	0.01 s–1
$f_{M,H}$	che-1 mRNA production rate upon induction by HD-TF	0.015 s–1
Models 1B, 2B
$f_H$	HD-TF protein production rate	0.0001 s–1
$b_H$	HD-TF protein degradation rate	0.000015 s–1