Table 2. Baseline characteristics associated with 3-month functional outcome.
| mRS 0-2 ( n = 960) | mRS 3-6 ( n = 524) | p | |
|---|---|---|---|
| Age, years | 70.8±11.5 | 77.8±9.9 | ＜0.001 |
| Sex, male | 640 (66.7) | 284 (54.2) | ＜0.001 |
| BMI, kg/m 2 ( n = 1,463) | 23.6±3.7 | 22.6±3.8 | ＜0.001 |
| Daily alcohol intake ( n = 1,459) | 310 (32.7) | 124 (24.3) | ＜0.001 |
| Current smoking ( n = 1,460) | 240 (25.3) | 73 (14.3) | ＜0.001 |
| Hypertension | 658 (68.5) | 371 (70.8) | 0.38 |
| Diabetes mellitus ( n = 1,483) | 336 (35.0) | 178 (34.0) | 0.73 |
| Dyslipidaemia ( n = 1,481) | 493 (51.4) | 241 (46.3) | 0.06 |
| Chronic kidney disease | 340 (35.4) | 249 (47.5) | ＜0.001 |
| Atrial fibrillation ( n = 1,483) | 156 (16.3) | 159 (30.4) | ＜0.001 |
| Previous stroke ( n = 1,483) | 238 (24.8) | 169 (32.3) | 0.002 |
| Previous ischaemic heart disease | 120 (12.5) | 84 (16.0) | 0.06 |
| NIHSS score at admission | 2 (1–4) | 7 (3–17) | ＜0.001 |
| Stroke subtype | ＜0.001 | ||
| Small-vessel occlusion | 281 (29.3) | 109 (20.8) | |
| Large-artery atherosclerosis | 242 (25.2) | 113 (21.6) | |
| Cardioembolic stroke | 211 (22.0) | 180 (34.4) | |
| Other aetiology | 226 (23.5) | 122 (23.3) | |
| Laboratory findings | 71 (29.3) | 49 (35.0) | |
| ALP levels U/l | 246.3±92.5 | 294.3±259.5 | ＜0.001 |
| CONUT ( n = 1,477) | 1 (0–2) | 2 (1–3) | ＜0.001 |
| GNRI ( n = 1,454) | 106.3 (100.1–112.8) | 100.4 (92.8–107.6) | ＜0.001 |
| NLR ( n = 1,479) | 2.6 (1.8–3.9) | 3.9 (2.3–6.6) | ＜0.001 |
| PLR ( n = 1,479) | 122.8 (93.8–168.4) | 142.6 (100.0–204.7) | ＜0.001 |
| CAR ( n = 1,470) | 0.04 (0.02–0.09) | 0.07 (0.03–0.34) | ＜0.001 |
Data are presented as the means±standard deviation for age, BMI, and each laboratory finding; as median (interquartile range) for NIHSS score at admission, CONUT, GNRI, NLR, PLR, and CAR; and as number of patients (%) for others. ALP, alkaline phosphatase; BMI, body mass index; NIHSS, National Institutes Health Stroke scale. CONUT, Controlling Nutritional Status; GNRI, Geriatric Nutritional Risk Index; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to- lymphocyte ratio; CAR, C reactive protein-to-albumin ratio