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. 2021 Dec 24;8:751793. doi: 10.3389/fmed.2021.751793

Table 1.

AKI diagnostic criteria.

Staging Urine volume Diagnostic criteria
RIFLE (2002) AKIN (2005) KIDGO (2012)
1 issue Urine output
<0.5 ml/kg/h
> 6 h
Risk: sCr elevated >
1.5 times
or GFR decline > 25%
sCr elevated ≥ 26.4
μmol/L
or elevated > 1.5–2.0 times the baseline value
sCr elevated ≥ 26.5 μmol/L (0.3 mg/dl) or elevated > 1.5–1.9 times the baseline value
2 issues Urine output
<0.5 ml/kg/h
> 12 h
Injury: sCr
elevated > 2 times
or GFR decline > 50%
sCr elevation > 2.0–3.0 times the baseline value Elevation > 2.0–2.9 times the baseline value
3 issues Urine output
<0.3 ml/kg/h
> 24 h
or no urine for >12 h
Failure: sCr
elevated > 3 times
or GFR decline > 75%
sCr ≥ 354 μmol/L
or an acute increase of
≥ 44 μmol/L Loss: persistent renal
failure > 4 weeks
ESRD: persistent renal failure > 3 months
sCr elevation > 3.0 times the baseline value

or sCr value ≥ 354 μmol/L
or an increase in acute sCr values ≥ 44 μmol/L
sCr elevated ≥353.6 μmol/L (4 mg/dl) or elevated > 3.0 times the baseline value
or starting kidney replacement therapy or <18-year-old patients with a decrease in eGFR to <35 ml/min/1.73 m2