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. 2021 Nov 26;30(1):42–52. doi: 10.1038/s41431-021-00984-w

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© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2021 2021

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Fig. 3 — a Families with variants in genes associated with nonsyndromic hearing loss. b Families with variants in genes associated with nonsyndromic hearing loss or Usher syndrome. Circles represent females and squares indicate males. Solid symbols represent individuals with bilateral severe-to-profound HL; non-shaded symbols represent unaffected individuals; crossed symbols represent deceased individuals. Individuals studied by exome sequencing are indicated by an asterisk, # indicates individuals whose gDNA was not available. The genotype for the candidate variant(s) are shown above each pedigree. + represents the reference allele; /, variants in trans. Only pedigrees with segregation information are presented.