Table 1.
Clinical characteristics of patients who underwent radical cystectomy for bladder cancer in the VHA from 2004 through 2018 stratified by baseline kidney function.
Baseline eGFR | eGFR <60 | eGFR ≥60 | Missing |
---|---|---|---|
No. of patients | 1081 | 2121 | 158 |
Age at surgery (yr), n (%) | 70.6 ± 7.9 | 65.9 ± 7.7 | 67.1 ± 8.7 |
≤59 | 91 (8.4) | 429 (20.2) | 33 (20.9) |
60–69 | 433 (40.1) | 1,101 (51.9) | 69 (43.7) |
70–79 | 418 (38.7) | 503 (23.7) | 41 (25.9) |
≥80 | 139 (12.9) | 88 (4.1) | 15 (9.5) |
Sex, n (%) | |||
Female | 7 (0.6) | 21 (1.0) | 3 (1.9) |
Male | 1074 (99.4) | 2100 (99.0) | 155 (98.1) |
Race, n (%) | |||
White | 937 (86.7) | 1815 (85.6) | 121 (76.6) |
Black | 91 (8.4) | 213 (10.0) | 25 (15.8) |
Other/unknown | 37 (3.4) | 49 (2.3) | 9 (5.7) |
Missing | 16 (1.5) | 44 (2.1) | 3 (1.9) |
Pathologic T stage, n (%) | |||
T0 | 22 (2.0) | 91 (4.3) | 3 (1.9) |
T1 | 94 (8.7) | 247 (11.6) | 23 (14.6) |
T2 | 207 (19.1) | 510 (24.0) | 26 (16.5) |
T3 | 273 (25.3) | 427 (20.1) | 34 (21.5) |
T4 | 161 (14.9) | 178 (8.4) | 25 (15.8) |
TA | 22 (2.0) | 37 (1.7) | 3 (1.9) |
CIS | 23 (2.1) | 65 (3.1) | 4 (2.5) |
Unknown | 229 (21.2) | 464 (21.9) | 34 (21.5) |
Missing | 50 (4.6) | 102 (4.8) | 6 (3.8) |
Pathologic N stage, n (%) | |||
N0 | 547 (50.6) | 1184 (55.8) | 78 (49.4) |
N1 | 70 (6.5) | 128 (6.0) | 13 (8.2) |
N2 | 127 (11.7) | 181 (8.5) | 19 (12.0) |
N3 | 14 (1.3) | 27 (1.3) | 4 (2.5) |
Unknown | 273 (25.3) | 501 (23.6) | 38 (24.1) |
Missing | 50 (4.6) | 100 (4.7) | 6 (3.8) |
Pathologic M stage, n (%) | |||
M0 | 368 (34.0) | 677 (31.9) | 61 (38.6) |
M1 | 18 (1.7) | 17 (0.8) | 7 (4.4) |
Unknown | 188 (17.4) | 315 (14.9) | 39 (24.7) |
Missing | 507 (46.9) | 1112 (52.4) | 51 (32.3) |
Charlson Comorbidity Index, n (%) | 6.3 ± 2.7 | 4.9 ± 2.5 | 5.2 ± 2.6 |
2 | 72 (6.7) | 408 (19.2) | 27 (17.1) |
3 | 80 (7.4) | 369 (17.4) | 24 (15.2) |
4 | 158 (14.6) | 337 (15.9) | 25 (15.8) |
5 | 173 (16.0) | 218 (10.3) | 22 (13.9) |
6+ | 598 (55.3) | 789 (37.2) | 60 (38.0) |
CIS = carcinoma in situ; eGFR = estimated glomerular filtration rate; VHA = Veterans Health Administration.