Fig 6.

qBEI analysis for BMDD and osteocyte lacunae. (A) qBEI images of Enpp1^wt mice and Enpp1^asj/asj mice treated with and without mEnpp1-Fc representing the calcium content of mineralized matrix. (B) BMDD curves show no differences between the three groups. (C–E). Determined parameters for mineralization, ie, CaMean, CaPeak and CaWidth, show no significant differences between the groups except reduced CaWidth in male Enpp1^asj/asj mice treated with mEnpp1-Fc compared with WT littermates. (F, G) Ot.Lc.Ar and N.Ot.Lc/B.Ar also show no significant differences.