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. 2022 Feb;12(2):1004–1019. doi: 10.21037/qims-21-705

Table 3. Comparison of PVS between the MS group and healthy control group.

PVS MS group (n=82) Control group (n=32) P value
PVS load
   PVS score 4 [3–4] 3 [3–4] 0.041
   Total number of PVSs 103.280±45.107 87.625±30.139 0.035
   Total number of EPVS 9 (4.75–17) 1 (0.25–2.75) <0.001
PVS distribution
   CSO-PVS 46.5 (27.75–63.5) 43 (34.25–60.5) 0.18
   BG-PVS 23.5 [15–36] 13 [7.25–16] <0.001
   Midbrain PVS 0 (0–1) 0 (0–0) 0.64
   Hippocampal PVS 1.5 (0–6) 2.5 (0–4.75) 0.892
EPVS distribution
   CSO-EPVS 3 [1–6] 0 (0–1) <0.001
   BG-EPVS 1 (0–3.25) 0 (0–0) <0.001
   Midbrain EPVS 0 (0–0) 0 (0–0) 0.068
   Hippocampal EPVS 0 (0–1) 0 (0–0) 0.068

MS, multiple sclerosis; PVS, perivascular space; EPVS, enlarged perivascular space; CSO, centrum semiovale; BG, basal ganglia.