Table 3. Comparison of PVS between the MS group and healthy control group.
PVS | MS group (n=82) | Control group (n=32) | P value |
---|---|---|---|
PVS load | |||
PVS score | 4 [3–4] | 3 [3–4] | 0.041 |
Total number of PVSs | 103.280±45.107 | 87.625±30.139 | 0.035 |
Total number of EPVS | 9 (4.75–17) | 1 (0.25–2.75) | <0.001 |
PVS distribution | |||
CSO-PVS | 46.5 (27.75–63.5) | 43 (34.25–60.5) | 0.18 |
BG-PVS | 23.5 [15–36] | 13 [7.25–16] | <0.001 |
Midbrain PVS | 0 (0–1) | 0 (0–0) | 0.64 |
Hippocampal PVS | 1.5 (0–6) | 2.5 (0–4.75) | 0.892 |
EPVS distribution | |||
CSO-EPVS | 3 [1–6] | 0 (0–1) | <0.001 |
BG-EPVS | 1 (0–3.25) | 0 (0–0) | <0.001 |
Midbrain EPVS | 0 (0–0) | 0 (0–0) | 0.068 |
Hippocampal EPVS | 0 (0–1) | 0 (0–0) | 0.068 |
MS, multiple sclerosis; PVS, perivascular space; EPVS, enlarged perivascular space; CSO, centrum semiovale; BG, basal ganglia.