Table 9. Correlation analysis of PVS and brain atrophy linear indexes in the acute attack MS group and the remission MS group.

Variables	rs/P	The acute attack MS group (n=59)				The remission MS group (n=23)
		PVS score	Total number of PVS	Total number of EPVS		PVS score	Total number of PVS	Total number of EPVS
Age	rs	0.349	0.401	0.359		0.387	0.278	−0.129
	P	0.007	0.002	0.005		0.068	0.198	0.557
Gender	rs	−0.045	−0.069	−0.168		−0.278	−0.197	−0.105
	P	0.734	0.601	0.205		0.2	0.368	0.633
Hypertension	rs	0.300	0.303	0.261		0.262	0.238	−0.175
	P	0.021	0.02	0.046		0.226	0.273	0.424
Recurrence times	rs	−0.082	−0.081	−0.151		0.015	−0.140	0.109
	P	0.535	0.540	0.253		0.946	0.523	0.621
Duration of disease (months)	rs	−0.035	−0.127	−0.161		−0.171	−0.178	0.037
	P	0.792	0.337	0.224		0.436	0.418	0.869
EDSS	rs	−0.002	−0.131	−0.189		−0.266	−0.173	−0.26
	P	0.990	0.321	0.153		0.220	0.431	0.231
CCI	rs	−0.017	0.077	0.102		0.146	0.372	−0.098
	P	0.896	0.560	0.444		0.505	0.080	0.656
CCA, cm2	rs	0.213	0.149	0.032		0.453	0.487	0.058
	P	0.105	0.260	0.808		0.030	0.019	0.791
Ratio of corpus callosum to cranium	rs	0.178	0.083	−0.03		0.325	0.479	−0.046
	P	0.179	0.533	0.822		0.130	0.021	0.835
u3VW, mm	rs	−0.106	−0.103	0.075		−0.069	−0.33	0.006
	P	0.425	0.437	0.571		0.753	0.124	0.979
a3VW, mm	rs	−0.110	−0.098	0.039		−0.140	−0.337	−0.024
	P	0.407	0.459	0.77		0.525	0.116	0.914
CCI*	rs	0.077	0.079	0.122		0.127	0.314	0.117
	P	0.567	0.557	0.365		0.584	0.166	0.614
CCA, cm2*	rs	0.144	0.075	0.031		0.313	0.419	0.301
	P	0.286	0.581	0.818		0.166	0.049	0.185
Ratio of corpus callosum to cranium*	rs	0.118	0.005	−0.012		0.279	0.414	0.259
	P	0.381	0.971	0.928		0.220	0.062	0.257

*, partial correlation analysis after adjusting for age and hypertension. MS, multiple sclerosis; PVS, perivascular space; EPVS, enlarged perivascular space; EDSS, extended disability status scale; CCI, corpus callosum index; CCA, corpus callosum area; CCR, ratio of the corpus callosum to the cranium; a3VW, aligned third ventricle width; u3VW, unaligned third ventricle width.