Figure 5.

Results of functional connectivity. The brain regions showing significantly decreased functional connectivity with the left dAI (A), the right PI (B), and left PI (C) in CD patients compared to HCs. CD, Crohn’s disease; HCs, healthy controls; dAI, dorsal anterior insula; PI posterior insula; pMCC/aMCC, posterior/anterior middle cingulate cortex; paraHIPP/HIPP, parahippocampus/hippocampus; ACC, anterior cingulate cortex; dlPFC, dorsolateral prefrontal cortex; S1, primary somatosensory; SMA, supplementary motor area.