Table 1. Disparities in clinicopathological features amongst patients with the high and limited nodal burden.
| Characteristic | Number (n=324) | Limited nodal burden (n=273) | High nodal burden (n=51) | χ2 | P value |
|---|---|---|---|---|---|
| Age, years | 0.033 | 0.856 | |||
| <50 | 118 (36.4) | 100 (36.6) | 18 (35.3) | ||
| ≥50 | 206 (63.6) | 173 (63.4) | 33 (64.7) | ||
| Family history of cancer | 0.414 | 0.520 | |||
| Absent | 305 (94.1) | 256 (93.8) | 49 (96.1) | ||
| Present | 19 (5.9) | 17 (6.2) | 2 (3.9) | ||
| Menopausal | 0.588 | 0.443 | |||
| No | 130 (40.1) | 112 (41.0) | 18 (35.3) | ||
| Yes | 194 (59.9) | 161 (59.0) | 33 (64.7) | ||
| Histologic type | – | 0.726* | |||
| Invasive ductal | 299 (92.3) | 250 (91.6) | 49 (96.1) | ||
| Invasive lobular | 7 (2.2) | 7 (2.6) | 0 | ||
| Others | 18 (5.6) | 16 (5.9) | 2 (3.9) | ||
| ER | 1.525 | 0.217 | |||
| Positive | 256 (79.0) | 219 (80.2) | 37 (72.5) | ||
| Negative | 68 (21.0) | 54 (19.8) | 14 (27.5) | ||
| PR | 0.026 | 0.873 | |||
| Positive | 238 (73.5) | 201 (73.6) | 37 (72.5) | ||
| Negative | 86 (26.5) | 72 (26.4) | 14 (27.5) | ||
| HER2 | 1.642 | 0.200 | |||
| Positive | 73 (22.5) | 58 (21.2) | 15 (29.4) | ||
| Negative | 251 (77.5) | 215 (78.8) | 36 (70.6) | ||
| Ki-67 | 6.377 | 0.014 | |||
| <20% | 154 (47.5) | 138 (50.5) | 16 (31.4) | ||
| ≥20% | 170 (52.5) | 135 (49.5) | 35 (68.6) | ||
| P53 | 2.916 | 0.088 | |||
| Positive | 228 (70.4) | 187 (68.5) | 41 (80.4) | ||
| Negative | 96 (29.6) | 86 (31.5) | 10 (19.6) | ||
| Molecular type | 5.654 | 0.130 | |||
| Luminal A | 118 (36.4) | 106 (38.8) | 12 (23.5) | ||
| Luminal B | 140 (43.2) | 115 (42.1) | 25 (49.0) | ||
| HER2 overexpression | 31 (9.6) | 23 (8.4) | 8 (15.7) | ||
| TNBC | 35 (10.8) | 29 (10.6) | 6 (11.8) | ||
| LVI | 25.977 | <0.001 | |||
| Absent | 244 (75.3) | 220 (80.6) | 24 (47.1) | ||
| Present | 80 (24.7) | 53 (19.4) | 27 (52.9) |
*, Fisher exact probability test results. Data presented as n (%). TNBC, triple negative breast cancer; LVI, lymphovascular invasion.