Table 2.

Summary of assessment for dostarlimab dose proportionality, part 1 cycle 1

Pharmacokinetic parameter	n	Slope
		Estimate	Standard error	90% CI
Cmax (µg/mL)	12	1.02	0.064	(0.91–1.13)
AUC(0-∞) (µg·h/mL)	11	0.91	0.11	(0.71–1.10)
AUC(0-τ) (µg·h/mL)	12	1.03	0.07	(0.90–1.15)

AUC area under the serum dostarlimab concentration–time curve, C_max maximum serum dostarlimab concentration