Fig. 2.

A multifunctional nanomedicine to enhance mPTT by HSP70 inhibition. (A) Schematic illustration of the synthesis of Qu-MP, possessing precise diagnosis, excellent mPTT efficacy, ROS scavenge, anti-inflammation, dynamic disassembly and renal clearance ability. (B) Changes of MCF-7 tumor volumes. (C) Images of excised tumors after various treatment (n = 4). (D, E) Immunofluorescence staining and western blot of the expression of HSP70 in tumors from mice 36 h after various treatments. 1: PBS, 2: quercetin, 3: Qu-Fe^IIP, 4: Qu-Fe^IIP + 808 nm laser (0.5 W/cm², 20 min). Scale bar: 200 µm. Reproduced with permission from [29]. Copyright 2019 Elsevier.