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. 2021 Oct 15;16(6):738–761. doi: 10.1016/j.ajps.2021.10.001

Fig. 9.

Fig 9

F–Pt-NPs-potentiated mPTT for reversing cascade cisplatin resistance. (A) Scheme of the preparation of F-NPs, Pt-NPs and F–Pt-NPs. (B) GSH consumption study via incubating GSH with Pt (IV) or P1 at different temperature for 15 h (***P< 0.001, **P< 0.01). (C) HPLC traces of Pt (IV) treated with GSH (10 × 10−3 M) at different temperature for 2 h; (D) Flow cytometry of F–Pt-NPs@Cy5.5 uptake after different treatment; (E) Quantification of Pt-DNA adducts by ICP-MS. Reproduced with permission from [81]. Copyright 2021 Wiley.