Table 2.

Quality assessment of the randomized controlled trials assessing the pharmacological management of RBD in adults

Summary of items from the NIH quality assessment tool (nhlbi.nih.gov): 1 = Randomized; 2 = Randomization adequate; 3 = Concealed; 4 = Blinding subjects; 5 = Blinding assessors; 6 = Groups matched at baseline; 7 = Overall dropout ≤ 20%; 8 = Differential dropout ≤ 15% between groups; 9 = Adherence to intervention; 10 = Other interventions avoided; 11 = Outcome assessed using valid and reliable measures; 12 = Sample size large enough for 80% power; 13 = outcomes and analyses pre-specified (registered); 14 = All received treatment allocated to. Green background with ‘✓’ = low risk of bias; Red background with ‘✕’ = high or unclear risk of bias