Fig. 2.

Reduced cancellous bone mass in mice lacking Panx1 in osteoclastic cells. μCT analyses were performed in the fifth lumbar vertebrae (A) and distal femur (B) from female and male Panx1^ΔOC mice and Panx1^fl/fl mice at 6 weeks of age. N = 6–8/group. Bars indicate means and lines standard deviations, and each dot corresponds to an individual sample. *: p < 0.05 vs. Panx1^fl/fl mice for the same sex. Representative μCT images for both sites are shown, scale bar corresponds to 0.25 mm.