Fig. 4.

Deletion of osteoclastic Panx1 results in higher osteoclastic parameters only in female mice. Static (A and B) and dynamic (C) histomorphometric parameters in cancellous bone of the second lumbar vertebrae of female and male mice at 6 weeks of age. N = 6–7/group. Bars indicate means and lines standard deviations, and each dot corresponds to an individual sample. *: p < 0.05 vs. Panx1^fl/fl mice for the same sex. Representative images are shown under the graphs. Scale bar = 20 μm.