Table 3.
Univariate and multivariate analyses for overall survival
| Factor | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Female (vs male) | 0.744 (0.396–1.284) | 0.3027 | 0.789 (0.416–1.383) | 0.4245 |
| Age ≥ 65 y (vs < 65 y) | 0.975 (0.659–1.433) | 0.8962 | 0.972 (0.655–1.437) | 0.8889 |
| pT 0–2 (vs pT 3–4) | 0.764 (0.517–1.125) | 0.1733 | 1.115 (0.720–1.725) | 0.6249 |
| pN 0–1 (vs pN 2–4) | 0.659 (0.448–0.970) | 0.0348 | 0.594 (0.391–0.902) | 0.0146 |
| LN (vs other organs) | 0.840 (0.571–1.245) | 0.3819 | 0.655 (0.405–1.066) | 0.0881 |
| Lung (vs other organs) | 0.647 (0.386–1.033) | 0.0687 | 0.529 (0.292–0.932) | 0.0274 |
| Solitary lesion (vs multiple) | 0.701 (0.453–1.122) | 0.1346 | 0.711 (0.408–1.332) | 0.2723 |
| Single organ (vs multiple) | 0.626 (0.350–1.241) | 0.1678 | 1.220 (0.511–2.983) | 0.6543 |
| Recurrence-free interval ≥ 550 days | 0.604 (0.365–0.956) | 0.0306 | 0.584 (0.348–0.941) | 0.0266 |
| R0 resection (vs R1 or R2) | 0.299 (0.190–0.487) | < 0.0001 | 0.389 (0.234–0.669) | 0.0009 |
| PC < IIIa (surgery for recurrence) | 0.384 (0.183–0.987) | 0.0472 | 0.352 (0.153–0.959) | 0.0420 |
PC Postoperative complication after surgical resection for recurrent lesion (Clavien–Dindo classification)