RNA of wild type endothelial cells was subjected to Sanger sequencing analysis after RT-PCR, which amplifies the selected B1 SINE elements. In the chromatographs of the sequencing, guanosine (G) peaks were seen together with adenosine (A) peaks. (A, B, C) Panel A shows the editing sites in the B1 element in the intron 14 of the Sppl2a gene (chr2: 126892815-126892950), whereas the editing sites in the 3′ UTR of the Nipa1 gene (chr7: 55977578-55977700) and the 3′ UTR of the Slfn5 gene (chr11: 82962556–82962680) are shown in panels (B and C). The sequences of each SINE are shown on the top with the editing sites highlighted. At the bottom are the corresponding sequencing chromatographs; the arrows indicate the editing sites.