Table 2.
Overview of the Percentage of Failure of Perichondrium Transplantation in Different Patient Groups a .
| Number of Knees | Fail, n (%) | Univariate |
Multivariate |
|||
|---|---|---|---|---|---|---|
| Hazard Ratio (95% CI) | P Value | Hazard Ratio (95% CI) | P Value | |||
| Total | 80 | 28 (35%) | ||||
| Number of lesions | ||||||
| Single lesion | 64 | 19 (42%) | 0.471 (0.213-1.043) | 0.064 | NA | NA |
| Multiple lesions b | 16 | 9 (56%) | ||||
| Patient age at time of surgery | ||||||
| Age <40 | 61 | 18 (30%) | 0.487 (0.225-1.058) | 0.069 | NA | NA |
| Age ≥40 b | 19 | 10 (53%) | ||||
| Lesion size | ||||||
| Size of the lesion <3 cm2b | 51 | 17 (33%) | ||||
| Size of the lesion ≥3 cm2 | 29 | 11 (38%) | 1.166 (0.999-1.361) | 0.051 | NA | NA |
| Previous surgery | ||||||
| Without previous surgery b | 19 | 2 (11%) | ||||
| With previous surgery | 61 | 26 (43%) | 4.894 (1.161-20.642) | 0.031* | 4.390 (1.036-18.598) | 0.045* |
| Duration of symptoms | ||||||
| Duration of symptoms <24 months b | 27 | 4 (15%) | ||||
| Duration of symptoms ≥24 months | 53 | 24 (45%) | 1.011 (1.004-1.018) | 0.001* | 1.010 (1.003-1.017) | 0.003* |
n = total number; % = percentage of the subgroup that failed; CI = confidence interval; NA = not applicable.
a
Parameters with a P value <0.100 in univariate Cox regression analysis were subsequently analyzed in an explorative multivariate cox regression analysis (italic text) stepwise excluding characteristics with the highest P value and definite multivariate Cox regression analysis was performed on the characteristics, “previous surgery” and “time of symptoms” (plain text).
b
Reference group.
*
Significant influence.