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. 2022 Jan 6;23:10. doi: 10.1186/s13059-021-02588-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Comparison of JAFFAL and LongGF on cancer cell line sequencing. Shown are ROC style curve with the ranking of previously validated fusions against other reported fusions for A MCF-7, HCT-116, A549, and K562 cell lines sequenced with ONT and B MCF-7, HCT-116, and SK-BR-3 cell lines sequenced with PacBio. C For MCF-7 only, high confidence fusions from JAFFAL (crosses) are compared against three short-read Illumina replicates (squares) across three sequencing depths (colors). D The overlap between fusions called by JAFFAL (high and low confidence) and LongGF (> 1 read support) on MCF-7