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The ratio of iNOS- and CD204-positive stained cells 72 h and 1 week after implantation. M2/M1 ratio around the bone formation area. The MSC-CM group showed a remarkable increase in the ratio both 72 h and 1 week after implantation. In the defect and PBS groups, the ratios were less than one because of the abundant iNOS-positive M1 macrophages.
