RA	rheumatoid arthritis
PCD	programmed cell death
AICD	activation-induced cell death
FLS	fibroblasts like synoviocytes
Bcl-2	B cell lymphoma/leukemia-2
Bax	accumulation of Bcl-2–associated X protein
Bak	Bcl-2 homologous antagonist/killer
Cyt c	cytochrome c
TNF	tumor necrosis factor
TNFR1	tumor necrosis factor receptor 1
STAT3	activators of transcription 3
HSP70	heat-shock-protein-70
PBL	peripheral blood lymphocyte
PADI4	peptidylarginine deiminase IV
NSAIDs	non-steroidal anti-inflammatory drugs
PPAR gamma	peroxisome proliferator-activated receptor gamma
IκB	the intracellular calcium, phosphorylated I-kappa-B
IKK	the intracellular calcium, phosphorylated I-kappa-B (IκB) kinase
NF-κB	nuclear factor kappa-light-chain enhancer of activated B cells
AA	adjuvant arthritis
TIPE2	TNF-alpha-induced protein-8-like-2
DR5	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2
MCL-1	myelogenous cell leukemia-1
Bim	Bcl-2 interacting mediator of cell death
SYVN1	the E3 ubiquitin ligase synoviolin
IRE1	inositol-requiring enzyme 1
CIA	collagen-induced arthritis
sFas	soluble Fas
mFas	membrane-bound Fas
ERK	extracellular signal-regulated kinase
PI3K	phosphatidylinositol 3-kinase
MMP	matrix metalloproteinase
IPT	imperatorin
TIMP-3	tissue inhibitor of metalloproteinases-3
CIP2A	cancerous inhibitor of protein phosphatase 2A
PDGF	platelet-derived growth factor
HIF-1α	hypoxia-inducible factor-1α
BAFF	B-cell activating factor
ASIC3	acid-sensing ion channel 3
TRPV1	transient receptor potential vanilloid 1
ROS	reactive oxygen species
NO	nitric oxide
TRPM8	transient receptor potential melastatin subtype 8
POGel	prolonged O2/Ca2+-supporting phototherapy hydrogel
CHOP	EBP-homologous protein
GA	Geldanamycin
PDCD5	programmed cell death 5
ALLN	calpain inhibitor 1
CBP	CREB binding protein
IAPs	inhibitors of apoptosis proteins
DC	dendritic cells
IL	Interleukin
RANKL	receptor activator of nuclear factor (NF)-κB ligand
TRAIL-R2	TNF-related apoptosis-inducing ligand-receptor 2
NADPH	nicotinamide adenine dinucleotide phosphate
PARP-1	poly (ADP-ribose) polymerase-1
CARD6	caspase recruitment domain protein 6
TRAF2	tumor necrosis factor receptor -associated factor-2
HOCl	hypochlorous acid
MPCs	mesenchymal progenitor cells
NETs	neutrophil extracellular traps
MPO	myeloperoxidase
NE	neutrophil elastase
CarP	carbamylated protein
chcap-18	cathelicidin human cationic antimicrobial protein-18
PAD	peptidylarginine deiminase
MHCII	MHC class II
LDG	low-density granulocytes
RF	rheumatoid factor
anti-CCP	anti-cyclic citrullinated peptide
ACPA	anti-citrullinated protein antibodies
AA	adjuvant-induced arthritis
RIPK	receptor-interacting protein kinase
MLKL	pseudokinase mixed lineage kinase domain-like
FAP-α	fibroblast activation protein-α
NHP	non-human primate
VDAC1	voltage-dependent anion-selective channel 1
ASICs	acid-sensitive ion channels
IFN-γ	interferon γ
SMAC	second mitochondria-derived activator of caspases
SMs	SMAC mimetics
PTX3	pentaxin 3
GSDMD	gasdermin D
PUN	punicalagin
mtDNA	mitochondrial DNA
PTPN2	phosphatase nonreceptor type 2
OA	osteoarthritis
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
SERCA	sarcoplasmic/endoplasmic reticulum Ca ATPase pump
AIA	adjuvant-induced arthritis
LC3b	light chain 3b
ULK-1	UNC51-like kinase 1
TLR	Toll-like receptor
GM-CSF	granulocyte-macrophage colony-stimulating factor
TGF	transforming growth factor
BID	the BH3 interacting-domain death agonist