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. 2021 Dec 24;12:728763. doi: 10.3389/fgene.2021.728763

TABLE 2.

Univariate and multivariate cox regression analyses on the correlations between NSCLC Patients’ clinicopathological factors and overall survival (OS) (Abbreviations: HR, hazard ratio; CI, confidence interval) (*p < 0.05).

Clinicopathological factors Comparison Univariate analysis Multivariate analysis
p value HR (95%CI) p value HR (95%CI)
Age (years) <65 vs. ≥65 0.567 0.8556 (0.5014–1.46)
Sex Male vs. Female 0.652 0.8692 (0.4726–1.599)
Smoker or not None vs. (Current and Formal) 0.135 1.555 (0.8713–2.776)
Tumor subtypes Adeno- vs. (Squamous-cell and Large cell) 0.810 1.062 (0.6519–1.73)
Tumor Clinical Stages I/II vs. III/IV 0.0395* 1.732 (1.027–2.921) 0.0073 1.634 (0.9547–2.796)
Tumor lymph-node Metastasis Positive vs. Negative 0.0074* 2.29 (1.249–4.2) 0.0025* 2.547 (1.3891–4.669)
Exosomal LINC00917 level Low and High 0.0016* 2.227 (1.352–3.669) 0.0038* 2.115 (1.2732–3.514)