(b).

Category		ID	Pathways	Associated genes	P-value
WT	0 h	/	/	/	/
	6 h	rno05320	Autoimmune thyroid disease	RT1-A2, RT1-CE7, GZMBL2, GZMB, FAS, RT1-BB	8.0E-04
		rno04066	HIF-1 signaling pathway	EGFR, CDKN1A, PFKFB3, HMOX1, SERPINE1, IFNG	2.8E-03
		rno04060	Cytokine-cytokine receptor interaction	IFNAR2, TNFRSF9, IFNG, CXCL9, EDAR, FAS, CXCL10	1.2E-02
		rno04620	Toll-like receptor signaling pathway	IFNAR2, JUN, CXCL9, LBP, CXCL10	1.4E-02
		rno04650	Natural killer cell mediated cytotoxicity	IFNAR2, GZMBL2, IFNG, GZMB, FAS	1.4E-02
		rno04152	AMPK signaling pathway	IRS2, CCND1, PFKFB3, CAB39, PCK1	3.4E-02
	24 h	rno03320	PPAR signaling pathway	CYP4A1, EHHADH, APOA5, FABP1, FABP7	5.0E-03
		rno00071	Fatty acid degradation	ECI1, CYP4A1, EHHADH, ADH6	8.6E-03
		rno04060	Cytokine-cytokine receptor interaction	CCL12, TNFSF10, LIFR, IL2RG, IL1A, CSF1R, ACVR1	8.9E-03
		rno04931	Insulin resistance	SREBF1, PTPRF, GFPT1, PIK3CA	7.7E-02
LBP−/−	0 h	rno03320	PPAR signaling pathway	ACOX2, CYP4A2, RXRA, CYP7A1, CYP8B1	7.6E-04
		rno00140	Steroid hormone biosynthesis	HSD17B2, CYP7A1, CYP2C7	7.1E-02
	6 h	rno01100	Metabolic pathways	CYP4A2, NAGS, NAT1, B3GALT4, ADH6, ACLY, FDFT1, CD38, PYCR2, UGT1A3, CYP4F6, GMPPA, FASN, LOC100912599, PAPSS1, CYP2A3	1.6E-02
		rno00071	Fatty acid degradation	CYP4A2, ADH6, CPT1A	3.8E-02
		rno03320	PPAR signaling pathway	CYP4A2, CPT1A, ANGPTL4	9.1E-02
	24 h	rno01100	Metabolic pathways	NADK2, SGPL1, QARS, COMT, PSPH, PNPLA3, GMPS, UMPS, ACSL1, GBE1, DPM3, LOC100912599, UGT2A3, ALG11, AMD1, FLAD1, CYP2C22	3.2E-02