Table 4.
Combinational diagnostic value of the markers for PJI
| Markers | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
| PLT combined with inflammatory markers | ||||
| PLT and ESR | 51.9 | 55.9 | 46.1 | 67.5 |
| PLT or ESR | 94.9 | 90.6 | 84.3 | 96.6 |
| PLT and CRP | 62.0 | 63.0 | 51.0 | 72.7 |
| PLT or CRP | 87.3 | 92.1 | 87.3 | 92.1 |
| PCT combined with inflammatory markers | ||||
| PCT and ESR | 63.3 | 57.5 | 48.1 | 71.6 |
| PCT or ESR | 93.7 | 91.3 | 87.1 | 95.9 |
| PCT and CRP | 64.6 | 52.0 | 45.5 | 70.2 |
| PCT or CRP | 87.3 | 90.3 | 82.1 | 91.8 |
| PMR combined with inflammatory markers | ||||
| PMR and ESR | 55.7 | 59.1 | 45.8 | 62.5 |
| PMR or ESR | 94.9 | 90.6 | 86.2 | 96.6 |
| PMR and CRP | 59.5 | 65.4 | 51.6 | 72.2 |
| PMR or CRP | 86.1 | 92.9 | 88.3 | 91.5 |
PJI, periprosthetic joint infection; CI, confidence interval; AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; PLT, platelet; PCT, plateletcrit; PMR, PLT to MPV ratio; MPV, mean platelet volume