TABLE 3.
The composition and proportion of DESs in the treatment of metabolic related diseases.
| DESs composition | Molar ratio | API | Diseases | References |
|---|---|---|---|---|
| Ibuprofen: Limonene | 1:4 | Limonene | Colon cancer | Pereira et al. (2019) |
| Choline chloride: Thiourea | 1:2 | 5-Fluorouracil | Multiple cancers | Mukesh et al. (2014) |
| Choline chloride | 2:1 | Bis-quinazolin-4-ones | Breast cancer | Ahmed et al. (2019) |
| L- (+)-tartaric acid | Lung cancer | |||
| Betaine: Mandelic acid | 1:1 | RA-XII | Multiple cancers | Liu et al. (2021) |
| Choline chloride: Malic acid | 2:1 | Insulin | Diabetes mellitus | Li et al. (2019) |
| Choline chloride: Malic acid | 2:1 | Insulin | Diabetes mellitus | Vaidya et al. (2020) |
| Choline chloride: Geranic acid | 1:2 | Insulin | Diabetes mellitus | Tanner et al. (2018) |
| Choline bicarbonate: Geranic acid | 1:1 | Insulin | Diabetes mellitus | Banerjee et al. (2017) |
| Choline chloride: Glycerol | 1:1 | Curcumin | Atherosclerosis | Jeliński et al. (2019) |
| Glucose:Sucrose | 1:1 | Curcumin | Atherosclerosis | Wikene et al. (2015) |