Table 1.
Main inflammation markers and vitamin D levels according to genotype in the total population.
| Gene | Genotype (n) | Age (yrs) | Fibrinogen (g/dL) | ESR (mm/h) | WBC (n103/mm3) | Platelets (n103/mm3) | 25-OH vit.D (nmol/L) |
|---|---|---|---|---|---|---|---|
| COL1A1 | |||||||
| ss (39) | 76.1 ± 7.0 | 373.5 ± 95.8 | 21.2 ± 20.2 | 6.1 ± 1.1 | 213.3 ± 57.5 | 78.9 ± 69.8 | |
| Ss (345) | 76.1 ± 7.5 | 360.5 ± 102.5 | 20.2 ± 19.7 | 5.8 ± 1.7 | 218.2 ± 62.8 | 81.5 ± 54.4 | |
| SS (688) | 76.5 ± 7.8 | 358.5 ± 87.7 | 21.7 ± 20.1 | 6.1 ± 2.7 | 219.4 ± 63.1 | 80.3 ± 52.6 | |
| VDR | |||||||
| ff (32) | 76.6 ± 8.1 | 386.3 ± 126.4 | 20.7 ± 23.9 | 6.4 ± 1.9 | 233.7 ± 59.7 | 62.2 ± 38.4∗ | |
| Ff (133) | 75.8 ± 7.2 | 378.9 ± 91.7 | 22.3 ± 21.9 | 5.6 ± 1.6 | 214.8 ± 60.2 | 73.5 ± 51.6 | |
| FF (136) | 75.9 ± 8.0 | 391.1 ± 89.8 | 21.2 ± 19.2 | 5.8 ± 1.7 | 225.7 ± 58.0 | 86.1 ± 54.7 | |
| CALCR | |||||||
| CC (86) | 75.7 ± 7.4 | 355.3 ± 82.3 | 22.9 ± 19.9 | 5.9 ± 1.7 | 218.4 ± 62.7 | 78.0 ± 44.6 | |
| CT (539) | 76.3 ± 7.7 | 346.7 ± 85.2 | 23.0 ± 23.6 | 6.2 ± 1.8 | 216.7 ± 61.6 | 87.2 ± 63.6 | |
| TT (813) | 76.0 ± 7.2 | 349.3 ± 153.5 | 21.3 ± 18.8 | 6.2 ± 2.3 | 218.2 ± 61.1 | 85.3 ± 59.6 | |
| ESR1-Pvu | |||||||
| pp (386) | 75.1 ± 7.1 | 357.5 ± 175.6 | 20.0 ± 16.4 | 6.2 ± 2.8 | 215.6 ± 58.1 | 82.1 ± 59.0 | |
| Pp (705) | 76.0 ± 7.6 | 357.0 ± 114.6 | 21.9 ± 21.1 | 6.2 ± 2.5 | 218.4 ± 58.8 | 84.5 ± 58.2 | |
| PP (249) | 76.3 ± 7.3 | 352.6 ± 104.3 | 22.4 ± 20.9 | 5.9 ± 1.5 | 211.0 ± 60.7 | 94.9 ± 63.1∗ | |
| ESR1-Xba | |||||||
| xx (476) | 75.4 ± 7.2 | 357.7 ± 161.7 | 20.7 ± 21.2 | 6.1 ± 2.6 | 213.2 ± 57.7 | 87.3 ± 61.3 | |
| Xx (684) | 76.1 ± 7.7 | 357.9 ± 117.5 | 22.0 ± 18.9 | 6.2 ± 2.5 | 220.0 ± 60.1 | 81.5 ± 56.3 | |
| XX (179) | 75.7 ± 6.8 | 346.7 ± 103.5 | 21.1 ± 19.8 | 6.0 ± 1.5 | 209.0 ± 56.5∗ | 98.7 ± 64.8∗ | |
Genes: CALCR = calcitonin receptor; COL1A = collagen type Iα1; ESR1 = estrogen receptor alpha; VDR = vitamin D receptor inflammation markers: ESR = erythrocyte sedimentation rate; WBC = white blood cells.
∗p < 0.05.