Table 1.
Comparisons of mean corpuscular volume (MCV), mean blood concentrations of hemoglobin (Hb), iron, vitamin B12, folic acid, and homocysteine between 42 high-titer (gastric parietal cell antibody or GPCA titer ≥ 160) GPCA-positive burning mouth syndrome (GPCA+BMS) patients or 67 low-titer (GPCA titer < 160) GPCA+BMS patients and 442 healthy control subjects as well as between 42 high-titer GPCA+BMS patients and 67 low-titer GPCA+BMS patients.
| Group | MCV (fL) | Hb (g/dL) |
Iron (μg/dL) |
Vitamin B12 (pg/mL) | Folic acid (ng/mL) | Homocysteine (μM) | ||
|---|---|---|---|---|---|---|---|---|
| Men | Women | Men | Women | |||||
| High-titer GPCA+BMS patients (n = 42) | 93.5 ± 8.8 | 13.5 ± 1.2 (n = 11) | 12.9 ± 1.1 (n = 31) | 73.6 ± 15.8 (n = 11) | 79.1 ± 24.8 (n = 31) | 324.1 ± 179.5 | 15.3 ± 6.1 | 14.5 ± 9.3 |
| aP-value | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.517 | <0.001 |
| bP-value | 0.086 | 0.147 | >0.999 | 0.003 | 0.050 | <0.001 | 0.684 | <0.001 |
| Low-titer GPCA+BMS patients (n = 67) | 90.6 ± 8.3 | 14.4 ± 1.7 (n = 15) | 12.9 ± 1.1 (n = 52) | 101.6 ± 25.1 (n = 15) | 91.0 ± 27.3 (n = 52) | 729.2 ± 247.9 | 14.8 ± 6.3 | 8.5 ± 3.1 |
| aP-value | 0.735 | 0.009 | <0.001 | 0.638 | 0.094 | 0.234 | >0.999 | 0.483 |
| Healthy control subjects (n = 442) | 90.4 ± 3.6 | 15.1 ± 0.8 (n = 106) | 13.5 ± 0.7 (n = 336) | 105.2 ± 28.0 (n = 106) | 97.8 ± 27.2 (n = 336) | 694.2 ± 220.2 | 14.7 ± 5.7 | 8.3 ± 2.0 |
a
Comparisons of means of parameters between 42 high-titer GPCA+BMS patients or 67 low-titer GPCA+BMS patients and 442 healthy control subjects by Student's t-test.
b
Comparisons of means of parameters between 42 high-titer GPCA+BMS patients and 67 low-titer GPCA+BMS patients by Student's t-test.