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. 2021 Dec 24;11:765842. doi: 10.3389/fcimb.2021.765842

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Copyright © 2021 Ray, Luis, Mishra, Barry, Asim, Pandey, Chaturvedi, Gupta, Gupta, Mahant, Das, Kumar, Shalimar, Wilson, Schneider and Chaturvedi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Meriva on growth of E. coli, Citrobacter rodentium, and H. pylori, and intracellular accumulation of curcumin and its derivatives. (A–C) Bacteria were grown in Brucella broth containing 20 µM Meriva or vehicle (ethanol), and growth was monitored by optical density for indicated time. (D–F) Bacteria were harvested and the concentration of curcumin, dihydro-(D-curc,DHC)-, tetrahydro-( T-curc-THC)-, hexahydro-(H-curc,HHC)- and octahydro-(O curc,OHC)-curcumin as well as bicyclopentadione (BCP) was quantified using LC-MS. ***P ≤ 0.001.