Figure 4.

Effect of curcumin and its stable analogs on growth of H. pylori and intracellular accumulation of bicyclopentadione (BCP) in H. pylori, E. coli, and Citrobacter rodentium (A) H pylori was grown in the absence or presence of curcumin, dimethyl-, acetal-, or diacetal-curcumin, and growth was determined by measuring optical density. (B) Intracellular accumulation of curcumin and BCP in H. pylori. (C) After 24hr treatment the ratio of accumulation of curcumin and BCP in E. coli, Citrobacter rodentium (Citro), and H. pylori (Hp). ^§§P ≤ 0.01.