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. 2021 Dec 24;12:782160. doi: 10.3389/fpsyg.2021.782160

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Copyright © 2021 Liu, Liou and Jou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Emotional state, (B) psychiatric symptoms, (C) behavioral disturbances, and (D) sleep disturbances of the two groups at different time points; for both the experimental and comparison groups, the domain with the maximum change was psychiatric symptoms. However, the change was not statistically significant (B). Continuous promising improvements were observed in sleep disturbances (D). The experimental group showed a significant improvement in sleep disturbances (Wald’s test = 3.9, P < 0.002; Wald’s test = 10.0, P = 0.04) from baseline to the 5th and 9th weeks compared with the comparison group.