Table 2.
Outcomes in patients with Acinetobacter baumannii infections, stratified by carbapenem susceptibility status
| Outcomes | Overall N = 5523 |
Carbapenem resistant N = 2047 |
Carbapenem susceptible N = 3476 |
P value |
|---|---|---|---|---|
| Overall LOSa | ||||
| Overall LOS, days, median (Q1–Q3) | 10 (6.0–18.0) | 11 (7.0–19.0) | 9 (6.0–17.0) | < 0.01 |
| Infection-associated LOSb | ||||
| Infection-associated LOS, days, median (Q1–Q3) | 8 (5.0–14.0) | 9 (5.0–14.0) | 8 (5.0–13.0) | < 0.01 |
| ICU utilization | ||||
| ICU admission during hospitalization, n (%) | 2845 (51.5) | 1276 (62.3) | 1569 (45.1) | < 0.01 |
| Index culture during ICU stay, n (%) | 2084 (37.7) | 927 (45.3) | 1157 (33.3) | < 0.01 |
| ICU-LOS, days, median (Q1–Q3)c | 6 (2.0–15.0) | 6 (3.0–14.0) | 6 (2.0–15.0) | 0.98 |
| Infection-associated ICU utilization | ||||
| Index culture during infection-associated ICU stay, n (%) | 2084 (37.7) | 927 (45.3) | 1157 (33.3) | < 0.01 |
| Infection-associated ICU-LOS, days, median (Q1–Q3)d | 5 (2.0–10.0) | 5 (2.0–10.0) | 5 (2.0–10.0) | 0.86 |
| Discharge status, n (%) | < 0.01 | |||
| Death | 683 (12.4) | 336 (16.4) | 347 (10.0) | |
| Home | 1992 (36.1) | 332 (16.2) | 1660 (47.8) | |
| Hospice | 236 (4.3) | 98 (4.8) | 138 (4.0) | |
| Other | 92 (1.7) | 14 (0.7) | 78 (2.2) | |
| Transfer to other facility | 2520 (45.6) | 1267 (61.9) | 1253 (36.1) |
ICU intensive care unit, LOS length of stay
aDefined as the number of days from admission to discharge date, regardless of discharge status
bDefined as the number of days from index culture date to discharge, regardless of discharge status
cDefined as the number of days from first to the last ICU service day, regardless of discharge status
dDefined as the number of days in ICU that was associated with the infection (i.e., index culture was taken within 2 days before ICU admission or during the ICU stay) and calculated as the following: (1) if a positive culture was obtained within 2 days of ICU admission, the entire ICU. LOS was used; (2) if the culture was obtained during ICU stay, the LOS was taken as the number of days from the ICU index culture to discharge from the ICU