Fig. 7.

Performance comparisons on different VAF distributions and difficult regions. a Performance analysis of different somatic callers on different VAF ranges across all replicates in the SEQC2 data sets. b Performance analysis of different somatic callers on difficult regions including tandem repeats (TR) of different sizes and segmental duplications. c Comparison of the F1-score (%) on the whole genome against the F1-score (%) on difficult genomic regions including tandem repeats (TR) of different sizes and segmental duplications