Table 2.

Univariable and multivariable cox proportional hazard regression models for overall survival

	Univariable			Multivariable
	HR	95% CI	P value	HR	95% CI	P value
Age (≥73)	1.63	1.17–2.29	0.0038	1.39	0.88–2.22	0.1574
initial PSA (≥450)	0.98	0.70–1.36	0.8942
GS ≥ 9	1.69	1.15–2.55	0.0068	1.62	0.98–2.75	0.0587
T stage (≥T3b)	1.68	1.11–2.62	0.0121	0.99	0.58–1.79	0.9800
N stage (positive)	2.07	1.42–3.09	0.0001	1.61	0.97–2.76	0.0643
Hb (<13)	1.60	1.14–2.25	0.0062	1.14	0.71–1.85	0.5915
LDH (≥ 208)	2.43	1.72–3.47	< 0.0001	2.54	1.61–4.11	< 0.0001
ALP (≥408)	1.76	1.25–2.49	0.0011	1.46	0.91–2.36	0.1145
NLR (≥2.6)	0.85	0.60–1.20	0.3521
CRP (≥0.2)	1.88	1.24–2.91	0.0030	1.41	0.87–2.32	0.1659

ALP, alkaline phosphatase; CI, confidence interval; CRP, C-reactive protein; GS, Gleason score sum; Hb, haemoglobin; HR, hazard ratio; LDH, lactate dehydrogenase; NLR, neutrophil-lymphocyte ratio; PSA, prostate-specific antigen.