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. 2020 Jul 21;11(6):776–782. doi: 10.1016/j.jpha.2020.06.009

Table 3.

Binding affinities of compounds isolated from AoEF for muscarinic acetylcholine receptor M3 (CHRM3).

No. Standard and compounds Binding affinity (kcal/mol)
S Loperamide (standard inhibitor) −16.7
1 1-Methylheptylbromide −6.1
2 2,2-Dimethyl 3 vinylbicylo (2,2,1) heptane −8.0
3 2,9-Dimethyldecane −7.9
4 3,7-Dimethyldecane −7.9
5 5-Chloropentanoic acid 2 methylphenyl ester −9.4
6 Oleic acid amide −9.6
7 7,10-Hexadecadienoic acid −9.5
8 9-Octadecenamide −9.9
9 9-Octadecenoic acid ethyl ester −10.6
10 11-Octadecenoic acid methyl ester −11.2
11 Anacardol −11.2
12 Docosanoic acid methyl ester −11.3
13 Dodecanol −7.4
14 Eicosanoic acid methyl ester −10.7
15 Hexacosanoic acid −11.3
16 N-decane −6.7
17 Oleic acid ethyl ester −10.2
18 Octadecanoic acid,2-(2-hydroxylethoxy)ethyl ester −12.3
19 Pentadecanoic acid −9.6
20 Stearic acid −10.6
21 Tetradecanamide −7.7
22 Tetradecanoic acid −9.1
23 Undecanoic acid −8.1
24 Oleic acid −9.7
25 Octadecanoic acid,2-hydroxylmethyl ester −12.1