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. 2022 Jan 6;21:3. doi: 10.1186/s12933-021-01443-y

Table 3.

Results of univariate Cox regression analysis

Variable All-cause mortality MACE
HR (95% CI) P value HR (95% CI) P value
Age 1.08 (1.02, 1.15) 0.0117 1.03 (0.98, 1.09) 0.2401
Male 1.05 (0.77, 1.43) 0.7774 1.15 (0.88, 1.51) 0.3181
BMI 0.96 (0.92, 1.00) 0.0839 0.98 (0.95, 1.02) 0.3472
SBP 0.99 (0.99, 1.00) 0.0581 0.99 (0.99, 1.00) 0.0105
DBP 0.99 (0.98, 1.01) 0.3366 1.00 (0.99, 1.01) 0.5432
LVEF 0.96 (0.95, 0.98)  < 0.0001 0.97 (0.96, 0.99)  < 0.0001
Gensini score 1.01 (1.00, 1.01)  < 0.0001 1.01 (1.00, 1.01)  < 0.0001
Hypertension 1.07 (0.76, 1.49) 0.7124 0.93 (0.71, 1.24) 0.6376
Diabetes 1.46 (1.10, 1.93) 0.0084 1.41 (1.11, 1.79) 0.0050
Hyperlipidemia 0.81 (0.57, 1.15) 0.2304 0.94 (0.71, 1.26) 0.6878
Previous MI 1.05 (0.75, 1.49) 0.7642 1.14 (0.85, 1.52) 0.3852
Previous stroke 1.50 (1.09, 2.04) 0.0116 1.54 (1.18, 2.01) 0.0014
CKD 2.30 (1.62, 3.25)  < 0.0001 1.81 (1.31, 2.48) 0.0003
Current smoking 1.08 (0.78, 1.48) 0.648 1.10 (0.84, 1.44) 0.4967
TC 1.26 (1.09, 1.45) 0.0015 1.14 (1.01, 1.29) 0.0295
TG 1.22 (1.03, 1.44) 0.0190 1.27 (1.09, 1.48) 0.0018
LDL-C 1.25 (1.06, 1.48) 0.0074 1.14 (0.99, 1.31) 0.0738
HDL-C 0.68 (0.44, 1.04) 0.0783 0.70 (0.49, 1.01) 0.0594
eGFR 0.98 (0.97, 0.98)  < 0.0001 0.99 (0.98, 0.99)  < 0.0001
FBG 1.05 (1.03, 1.06)  < 0.0001 1.04 (1.02, 1.06)  < 0.0001
UA 1.00 (1.00, 1.00) 0.0035 1.00 (1.00, 1.00) 0.0160
TyG index 1.75 (1.42, 2.16)  < 0.0001 1.60 (1.32, 1.92)  < 0.0001
Aspirin 0.38 (0.21, 0.70) 0.0019 0.43 (0.25, 0.75) 0.0031
Clopidogrel 0.60 (0.34, 1.05) 0.0711 0.63 (0.39, 1.03) 0.0653
Statin 0.98 (0.59, 1.64) 0.9511 1.40 (0.86, 2.30) 0.1785
β-blocker 1.06 (0.80, 1.42) 0.6721 1.23 (0.96, 1.59) 0.1021
ACEI/ARB 1.11 (0.84, 1.48) 0.4501 1.13 (0.89, 1.43) 0.3199
LM lesion 1.53 (1.09, 2.14) 0.0141 1.78 (1.34, 2.35)  < 0.0001
Multivessel lesion 1.44 (1.04, 2.00) 0.0299 1.62 (1.22, 2.15) 0.0009

P values in bold are < 0.05

BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVEF, left ventricular ejection fraction; MI, myocardial infarction; CKD, chronic kidney disease; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein-C; HDL-C, high-density lipoprotein-C; eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; UA, uric acid; TyG, triglyceride glucose; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; LM, left main coronary artery