Fig. 2.

Differentially abundant mRNAs and miRNAs. (A) Volcano plot of differentially abundant mRNAs in ovarian cancer (n = 26) versus controls (n = 48). Upregulated genes with an adjusted p-value of less than 0.05 are shown in pink. No downregulated genes are detected. (B) Volcano plot of differentially abundant miRNAs in ovarian cancer (n = 26) versus controls (n = 48). Upregulated miRNAs with an adjusted p-value of less than 0.05 are shown in pink. No downregulated miRNAs are detected. (C) Boxplots comparing the Sequin spike normalized read counts per group for the top 20 most differentially abundant genes. The normalized read count per sample is shown as a dot. Samples obtained from ovarian cancer patients are pink, samples obtained from controls are blue. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article).