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. 2022 Jan 6;20:24. doi: 10.1186/s12951-021-01232-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 9 — a General structure of dual NIR-II probes and NIR-II imaging-guided sentinel lymph nodes resection. b Schematic illustration of dual NIR II fluorescent dye injection and lymphatic drainage. c The illustration of dual-color imaging-guided surgery. d The different channels images displayed signal accumulation of IR-FD and QDs after administration of subcutaneous injection in tumor bearing mouse. e Dual NIR-II imaging guided pre- and post-surgery of sentinel LN excision. Reproduced with permission from [134]. Copyright 2020, Wiley–VCH Verlag GmbH & Co. KGaA, Weinheim