KEY RESOURCES TABLE
| Resource Type | Specific Reagent or Resource | Source or Reference | Identifiers | Additional Information |
|---|---|---|---|---|
| Add additional rows as needed for each resource type | Include species and sex when applicable. | Include name of manufacturer, company, repository, individual, or research lab. Include PMID or DOI for references; use “this paper” if new. | Include catalog numbers, stock numbers, database IDs or accession numbers, and/or RRIDs. RRIDs are highly encouraged; search for RRIDs at https://scicrunch.org/resources. | Include any additional information or notes if necessary. |
| Antibody | Mouse anti-tyrosine hydroxylase | Abcam | Cat#AB129991; RRID: AB_11156128 | |
| Antibody | Chicken anti-GFP | Abcam | Cat#AB13970; RRID: AB_300798 | |
| Antibody | Rabbit anti-RFP | Rockland | Cat#600-401-379; RRID:AB_2209751 | |
| Antibody | Rabbit anti-pCREB S133 | Abcam | Cat#AB32096; RRID:AB_731734 | |
| Antibody | Goat anti-rabbit Alexa 488/647 | Thermo Fisher Scientific | Cat#A-11034/21244; RRID: AB_2576217, RRID: AB_2535812 | |
| Antibody | Goat anti-chicken Alexa 488 | Thermo Fisher Scientific | Cat# A-11039; RRID:AB_2534096 | |
| Antibody | Goat anti-mouse Alexa 594 | Thermo Fisher Scientific | Cat# A-11032; RRID:AB_2534091 | |
| Bacterial or Viral Strain | AAV1.CBA.DIO.hM4Di.mCherry | Hou XH, 2016 Packaged by Vigene (Plasmid, Dr. Sabatini) | Addgene plasmid # 81008 | |
| Bacterial or Viral Strain | AAV8.CAG.Flex.EGFP | UNC Vector Core (Dr. Boyden) | N/A | |
| Bacterial or Viral Strain | AAV1.hSyn.Cre.WPRE.Hgh | Penn vector core (Dr. Wilson) | ddgene viral prep # 105553-AAV1 Penn ID: AV-1-PV2676 | |
| Bacterial or Viral Strain | AAV1.EF1a.DIO.hChR2(H134R).eYFP | Penn vector core (Dr. Deisseroth) | Addgene viral prep # 20298-AAV1, RRID:Addgene_20298 | |
| Bacterial or Viral Strain | AAV1.CBA.DIO.rM3Ds.mCherry.WPRE | Packaged by Vigene (Plasmid, Dr. Roth) | Addgene plasmid # 50458 Custom cloning | |
| Bacterial or Viral Strain | AAV1.FLEX.PKI.IRES.nls.mRuby2 | Chen et al, 2014 Packaged by Vigene (Plasmid, Dr. Sabatini) | Addgene plasmid # 63059 | |
| Chemical Compound or Drug | Ketamine | Vedco | 217-484-6; CAS: 1867-66-9 | |
| Chemical Compound or Drug | Clozapine-N-oxide | Sigma-Aldrich | C0823; CAS: 34233-69-7 | |
| Chemical Compound or Drug | SKF-83566 hydrobromide | Tocris | 1586; CAS: 108179-91-5 | |
| Chemical Compound or Drug | MNI-caged-L-glutamate | Tocris | 1490; CAS: 295325-62-1 | |
| Chemical Compound or Drug | SKF 81297 hydrobromide | Tocris | 1447; CAS 67287-39-2 | |
| Chemical Compound or Drug | H-89 dihydrochloride | Tocris | 2910; CAS 130964-;39-5 | |
| Commercial Assay Or Kit | RNAscope Fluorescence Multiplex Assay | ACDBio | Cat No. 320850 | |
| Commercial Assay Or Kit | RNAscope Probe- Mm-drd1a | ACDBio | Cat No. 406491-C2 | |
| Commercial Assay Or Kit | RNAscope Probe- egfp | ACDBio | Cat No. 409971 | |
| Deposited Data; Public Database | Raw and analyzed data | This paper | ||
| Organism/Strain | Mouse: C57BL/6 | Charles River | Cat#000664; RRID: IMSR_JAX:000664 | |
| Organism/Strain | Mouse: B6.SJL-S1c6a3tm1.1(cre)Bkmn/J | Jackson Laboratory | Cat#006660; RRID: IMSR_JAX:006660 | |
| Organism/Strain | Mouse: B6.FVB(Cg)-Tg(Drd1a-cre)FK150Gsat/Mmucd | Jackson Laboratory | RRID:MMRRC_036916-UCD | |
| Organism/Strain | Mouse: STOCK Drd1tm2.1St1/J | Jackson Laboratory | Cat#025700; RRID: IMSR_JAX:025700 | |
| Recombinant DNA | pAAV-hSyn-DIO-rM3D(Gs)-mCherry | Addgene | Cat#50458 | |
| Recombinant DNA | pAAV-CBA-DIO-WPRE-hGH Backbone | Addgene | Cat#81008 | |
| Software; Algorithm | GraphPad Prism 7 | GraphPad | RRID: SCR_002798 | |
| Software; Algorithm | FIJI | Schindelin et al., 2012 | http://fiji.sc/; RRID: SCR_002285 | |
| Software; Algorithm | MATLAB | MathWorks | RRID: SCR_001622 | |
| Software; Algorithm | Igor Pro | WaveMetrics | RRID: SCR_000325 | |
| Software; Algorithm | Toxtrac | Rodriguez, A., et al., 2018 | N/A | |
| Software; Algorithm | Python | Python Software Foundation | RRID:SCR_008394 | |
| Software; Algorithm | CANDLE | The McConnell Brain Imaging Centre Coupé, P., et al., 2012 | N/A | |
| Software; Algorithm | Neurolucida 360 | MBF Bioscience | RRID:SCR_016788 | |
| Other | Active/Passive Avoidance Shuttle Box | MazeEngineers | https://mazeengineers.com/portfolio/active-passive-avoidance-shuttle-box/#description | |
| Other | Raspberry Pi | Raspberry Pi Foundation | https://www.raspberrypi.org/ |