Table 3B.
Vessel and lesion characteristics between concordant and discordant cases of RFR and FFR.
|
RFR > 0.89 FFR > 0.8 Both negative |
RFR ≤ 0.89 FFR > 0.8 Discordance |
RFR ≤ 0.89 FFR ≤ 0.8 Both positive |
RFR > 0.89 FFR ≤ 0.8 Discordance |
p value | Concordance | Discordance | p value | |
|---|---|---|---|---|---|---|---|---|
| No. of vessels | 396 (55.7) | 94 (13.2) | 159 (22.3) | 63 (8.8) | 555 (78.0) | 157 (22.0) | ||
| Target Vessel | ||||||||
| Left anterior descending | 174 (43.9) | 75 (79.8) | 131 (82.4) | 44 (69.8) | < 0.01 | 305 (55.0) | 119 (75.8) | < 0.01 |
| Ramus intermedius | 7 (1.8) | 2 (2.1) | 2 (1.3) | 0 (0) | 0.70 | 9 (1.6) | 2 (1.3) | 0.76 |
| Right coronary artery | 108 (27.3) | 8 (8.5) | 10 (6.3) | 17 (27) | < 0.01 | 118 (21.3) | 25 (15.9) | 0.14 |
| Left circumflex artery | 98 (24.7) | 9 (9.6) | 15 (9.4) | 2 (3.2) | < 0.01 | 113 (20.4) | 11 (7) | < 0.01 |
| Number of diseased vessels total | ||||||||
| 1 | 94 (23.7) | 25 (26.6) | 28 (17.6) | 11 (17.5) | 0.23 | 122 (22) | 36 (22.9) | 0.80 |
| 2 | 159 (40.2) | 33 (35.1) | 51 (32.1) | 29 (46) | 0.16 | 210 (37.8) | 62 (39.5) | 0.71 |
| 3 | 120 (30.3) | 34 (36.2) | 78 (49.1) | 23 (36.5) | < 0.01 | 198 (35.7) | 57 (36.3) | 0.88 |
| Lesion location | ||||||||
| Proximal | 191 (48.2) | 39 (41.5) | 58 (36.5) | 20 (31.7) | 0.02 | 249 (44.9) | 59 (37.6) | 0.11 |
| Mid | 147 (37.1) | 47 (50.0) | 74 (46.5) | 32 (50.8) | 0.03 | 221 (39.8) | 78 (49.7) | 0.03 |
| Distal | 58 (14.6) | 8 (8.5) | 27 (17) | 11 (17.5) | 0.27 | 85 (15.3) | 19 (12.1) | 0.31 |
| Non-focal lesion | 136 (34.3) | 49 (52.1) | 81 (50.9) | 24 (38.1) | < 0.01 | 217 (39.1) | 73 (46.5) | 0.10 |
| QCA analysis | ||||||||
| Diameter stenosis, % | 49.45 ± 7.26 | 51.69 ± 7.43 | 59.07 ± 8.1 | 61.04 ± 6.96 | < 0.01 | 52.2 ± 8.68 | 55.44 ± 8.56 | < 0.01 |
| Reference diameter, mm | 3.12 ± 0.61 | 2.9 ± 0.61 | 2.76 ± 0.57 | 2.79 ± 0.56 | < 0.01 | 3.02 ± 0.62 | 2.86 ± 0.59 | 0.01 |
| Minimal lumen diameter, mm | 1.58 ± 0.39 | 1.41 ± 0.39 | 1.13 ± 0.31 | 1.12 ± 0.32 | < 0.01 | 1.46 ± 0.42 | 1.3 ± 0.39 | < 0.01 |
| Lesion length, mm | 14.27 ± 8.53 | 14.61 ± 9.17 | 18.07 ± 10.96 | 19.46 ± 10.25 | < 0.01 | 15.36 ± 9.44 | 16.56 ± 9.88 | 0.17 |
| Pressure wire-derived index | ||||||||
| FFR | 0.89 (0.86–0.93) | 0.84 (0.82–0.86) | 0.75 (0.71–0.78) | 0.78 (0.76–0.8) | < 0.01 | 0.86 (0.79–0.91) | 0.82 (0.79–0.85) | < 0.01 |
| RFR | 0.95 (0.93–0.98) | 0.88 (0.85–0.89) | 0.85 (0.81–0.87) | 0.92 (0.91–0.93) | < 0.01 | 0.93 (0.88–0.97) | 0.89 (0.87–0.91) | < 0.01 |
| dPR[WFP] | 0.96 (0.93–0.98) | 0.88 (0.86–0.89) | 0.85 (0.81–0.87) | 0.92 (0.91–0.94) | < 0.01 | 0.94 (0.88–0.97) | 0.89 (0.87–0.91) | < 0.01 |
| dPR[diastole] | 0.96 (0.93–0.98) | 0.88 (0.86–0.90) | 0.86 (0.82–0.88) | 0.92 (0.91–0.94) | < 0.01 | 0.94 (0.89–0.98) | 0.90 (0.88–0.92) | < 0.01 |
| Resting Pd/Pa | 0.96 (0.95–0.99) | 0.91 (0.9–0.92) | 0.88 (0.85–0.9) | 0.94 (0.92–0.95) | < 0.01 | 0.95 (0.91–0.98) | 0.92 (0.9–0.94) | < 0.01 |
Data are presented as n (%), mean SD, or median (Q1–Q3); Abbreviations as in the text. Bold numbers represent statistically significant p values.