Table 4A.
Independent predictors of disagreement between RFR and FFR.
| Discordance with RFR ≤0.89 and FFR >0.8 | ||||||
|---|---|---|---|---|---|---|
| Univariate Analysis | Multivariate Analysis | |||||
| Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value | |
| Age, per 1-year increment | 1.04 | 1.02–1.07 | < 0.01 | 1.04 | 1.02–1.07 | 0.01 |
| Female | 1.86 | 1.19–2.92 | 0.01 | 1.70 | 1.06-2.74 | 0.03 |
| Diabetes mellitus | 0.99 | 0.6–1.61 | 0.96 | |||
| Hypertension | 1.06 | 0.65–1.74 | 0.80 | |||
| Hyperlipidemia | 1.24 | 0.8–1.92 | 0.33 | |||
| Current or former smoking | 1.21 | 0.77–1.89 | 0.41 | |||
| Peripheral arterial disease | 2.42 | 1.29–4.54 | 0.01 | 2.71 | 1.39–5.28 | 0.01 |
| NSTEMI or unstable AP | 0.97 | 0.59–1.59 | 0.91 | |||
| Previous PCI in target vessel | 1.33 | 0.81–2.19 | 0.26 | |||
| Previous myocardial infarction | 1.12 | 0.70–1.80 | 0.64 | |||
| Non-focal lesion | 1.70 | 1.10–2.63 | 0.02 | 1.84 | 1.17–2.89 | 0.01 |
| Multivessel disease | 0.85 | 0.53–1.38 | 0.52 | |||
| Proximal or mid segment* | 1.98 | 0.93–4.21 | 0.08 | |||
| Proximal segment | 0.93 | 0.60–1.44 | 0.73 | |||
| Mid segment | 1.38 | 0.90–2.14 | 0.14 | |||
| Distal segment | 0.51 | 0.24–1.08 | 0.08 | |||
| % DS | 0.98 | 0.96–1.01 | 0.14 | |||
| Minimal lumen diameter | 0.96 | 0.58–1.62 | 0.89 | |||
| Lesion length | 0.99 | 0.96–1.01 | 0.27 | |||
| Lesion location LAD | 3.04 | 1.8–5.16 | < 0.01 | 3.22 | 1.88–5.52 | < 0.01 |
| Lesion location RCA | 0.33 | 0.16–0.7 | < 0.01 | |||
| Lesion location LCX | 0.46 | 0.23–0.95 | 0.04 | |||
*
Target lesion located in the proximal or mid segment of the target vessel. CI, confidence interval; other abbreviations as in the text. Bold numbers represent statistically significant p values.